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UV Medico offers a solution for allowing fully gowned operators to enter cleanrooms without any microbial contamination on their gown, mask, goggles, or other equipment.

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Our Far-UVC solution for healthcare facilities and hospitals offers ongoing and efficient decontamination without interrupting patient care.

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Reduce the likelihood of disease spread when patients and medical personnel are in the ambulance. Our solution ensures effective decontamination of the patient area.

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Airborne diseases constantly threaten public health. Combat these risks effectively by enhancing indoor air quality with the installation of UV222.

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1 min read

222nm UVC Light: Safe and Effective Bacterial Killer in Human Trials

222nm UVC Light: Safe and Effective Bacterial Killer in Human Trials

Introduction: Surgical site infection is one of the most severe complications of surgical treatments. However, the optimal procedure to prevent such infections remains uninvestigated. Ultraviolet radiation C (UVC) with a short wavelength has a high bactericidal effect; however, it is cytotoxic. Nonetheless, given that UVC with a wavelength of 222 nm reaches only the stratum corneum, it does not affect the skin cells. This study aimed to investigate the safety of 222-nm UVC irradiation and to examine its skin sterilization effect in healthy volunteers.

Methods: This trial was conducted on 20 healthy volunteers. The back of the subject was irradiated with 222-nm UVC at 50–500 mJ/cm2, and the induced erythema (redness of skin) was evaluated. Subsequently, the back was irradiated with a maximum amount of UVC not causing erythema, and the skin swabs before and after the irradiation were cultured. The number of colonies formed after 24 hours was measured. In addition, cyclobutene pyrimidine dimer (CPD) as an indicator of DNA damage was measured using skin tissues of the nonirradiated and irradiated regions.

Results: All subjects experienced no erythema at all doses. The back of the subject was irradiated at 500 mJ/cm2, and the number of bacterial colonies in the skin swab culture was significantly decreased by 222-nm UVC irradiation. The CPD amount produced in the irradiated region was slightly but significantly higher than that of the non-irradiated region.

Conclusion: A 222-nm UVC at 500 mJ/cm2 was a safe irradiation dose and possessed bactericidal effects. In the future, 222-nm UVC irradiation is expected to contribute to the prevention of perioperative infection.

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