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Cleanroom

UV Medico offers a solution for allowing fully gowned operators to enter cleanrooms without any microbial contamination on their gown, mask, goggles, or other equipment.

Far-UVC Cleanroom Solutions

Healthcare

Our Far-UVC solution for healthcare facilities and hospitals offers ongoing and efficient decontamination without interrupting patient care.

Far-UVC Healthcare Solutions

Ambulances

Reduce the likelihood of disease spread when patients and medical personnel are in the ambulance. Our solution ensures effective decontamination of the patient area.

Far-UVC Ambulace Solutions

Indoor Air Quality

Airborne diseases constantly threaten public health. Combat these risks effectively by enhancing indoor air quality with the installation of UV222.

Far-UVC Indoor Air Quality Solutions

1 min read

Evaluating Corneal Damage from 222-nm and 254-nm UV Light in Rats

Evaluating Corneal Damage from 222-nm and 254-nm UV Light in Rats

222nm ultraviolet (UV) light produced by a krypton–chlorine excimer lamp is harmful to bacterial cells but not to skin. However, the effects of 222-nm UV light exposure on the eye are not fully known. We evaluated acute corneal damage induced by 222- and 254-nm UV light in albino rats. Under deep anesthesia, 6-week-old Sprague–Dawley albino rats were exposed to UV light.

The exposure levels of corneal radiation were 30, 150, and 600 mJ/cm2. Epithelial defects were detected by staining with fluorescein. Superficial punctate keratitis developed in corneas exposed to more than 150mJ/cm2 of UV light, and erosion was observed in corneas exposed to 600mJ/cm2 of UV light. Haematoxylin and eosin staining also showed corneal epithelial defects in eyes exposed to 254-nm UV light. However, no damage developed in corneas exposed to 222-nm UV light. Cyclobutane pyrimidine dimer-positive cells were observed only in normal corneas and those exposed to 254-nm UV light.

Although some epithelial cells were stained weakly in normal corneas, squamous epithelial cells were stained moderately, and the epithelial layer that was detached from the cornea exposed to 600mJ/cm2 of light was stained intensely in corneas exposed to 254-nm UV light.

In the current study, no corneal damage was induced by 222-nm UV light, which suggested that 222-nm UV light may not harm rat eyes within the energy range and may be useful for sterilising or preventing infection in the future.