Minimal, superficial DNA damage in human skin from filtered far-ultraviolet-C (UV-C)

We performed human skin irradiation in two settings using a filtered KrCl far‐UVC source (SafeZoneUVC, Ushio Inc., Tokyo, Japan): firstly, in a novel ex vivo full‐thickness human skin model cultured at tension (manuscript in preparation) and secondly, using in vivo self‐exposures.’

This first‐in‐human demonstration of CPD location from filtered far‐UVC confirms the results of our previous in silico model and indicates that the peak KrCl excimer emission wavelength of 222 nm does not penetrate beyond the most superficial epidermal layers. … However, to date, the evidence is overwhelmingly in favour of using filtered far‐UVC as a safe, effective germicidal technology.

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