UVC Light: A Safer Alternative for Reducing Surgical Site Infections
UV Medico
:
Mar 5, 2024 10:02:51 AM

Key Findings:
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Impact of 254-nm UVC:
- Induces significant DNA damage in microorganisms and human cells, with marked CPD formation in mammalian cells.
- Chronic exposure causes sunburn, skin desquamation, hyperplasia, and intercellular edema in mice.
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Effectiveness and Safety of 222-nm UVC:
- Demonstrates bactericidal properties without inducing mutagenic or cytotoxic DNA damage in mammalian cells, even with chronic exposure.
- Detected CPDs are limited to the hyperkeratotic stratum corneum (superficial skin layer).
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Clinical Relevance:
- 222-nm UVC emerges as a safer alternative to 254-nm UVC for reducing surgical site infections (SSIs).
- Offers promising applications in healthcare, minimizing risks for patients and hospital staff.
This study reinforces 222-nm UVC as a viable, human-safe tool for continuous infection control in surgical and hospital environments.
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